Differential expression of subunits in DRG neurons
نویسندگان
چکیده
Background: Auxiliary subunits regulate the voltage-gated sodium channels of DRG neurons. Results: subunits are differentially expressed in subpopulations of DRG neurons and regulate Nav1.7 channels in an isoform-specific manor. Conclusions: Differential subunit expression and isoform-specific regulation has important implications for the sodium currents of DRG neurons. Significance: subunits are important determinants of sodium channel function and sensory neuron excitability.
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